Influence of Doxapram Hydrochloride on Recovery from Thiopental Anaesthesia.

نویسندگان

  • W EVERS
  • K MALIK
  • A B DOBKIN
چکیده

MAN~ DaWS known as respiratory stimulants have been covely from pmsonmg by barbiturates and other sedat:ve have also been used to inmate and sustain breathing accelerate the rate of recovery from general anaesthes:a mon practice m years past has been to add carbon dmnl, of an anaesthetac to accomphsh this goal Even thoug prachces may be inherently dangerous, they are still used Recently, several new drugs have been developed wincl and may accelerate recovery from anaesthesm with far ducmg dangerous wntataon of the gastrointestinal tract tract (coughing, sneezing), or neuromuscular system (m s:ons) 3~ Some of these drugs are now being used effech of chromc mcapacatatmg lung diseases, and they may respiratory depressmn produced by analges:cs 7-~o Alth~ short durataon when gwen as a single mlectmn, they m~ the respiratory centres to the arterial blood pCO.. durra ratory dep:essmn and may be useful m this cond:tion, continuous mfusmn rather than as a single mlectmn 3 ~ 1: used to accelerate redrugs These stimulants n the newborn, and to Perhaps the most comte mhalatmn at the end : many feel that these 2

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Analeptic Effects of Doxapram Hydrochloride on Thiopentone Induced Depression.

A study of the analeptic properties of doxapram hydrochloride, as judged by its effects on the depression induced by moderate doses of thiopentone, was carried out in sixty patients. Three dose levels of the drug were employed, all of which produced marked increases in alveolar ventilation. These increases were due almost entirely to effects on tidal volume. Although the initial peak of stimula...

متن کامل

Evaluation of doxapram for arousal from general anaesthesia in outpatients.

In a double-blind study of 100 outpatients receiving methohexitone, nitrous oxide and halothane, the administration of doxapram 80 mg i.v. was associated with a significantly more rapid recovery from anaesthesia, the effect being more obvious in women than men. Doxapram produced a reduction of 3-4 min in the time of recovery to a safe level of consciousness. The effect was probably a result of ...

متن کامل

Effect of doxapram on the rate of recovery from atracurium and vecuronium neuromuscular block.

We have studied the effect of doxapram on the rates of spontaneous and neostigmine-induced recovery from neuromuscular block with atracurium and vecuronium, by measurement of the time to recovery of T1 (first twitch in the train-of-four) from 25 to 75% of control (recovery index, RI). After each neuromuscular blocking drug, RI was measured without administering either doxapram or neostigmine (c...

متن کامل

Effect of doxapram on neostigmine evoked antagonism of vecuronium neuromuscular block.

We have examined the effect of doxapram on neostigmine-evoked antagonism of vecuronium neuromuscular block in a double-blind study in anaesthetized patients. Neuromuscular transmission was measured with a Datex Relaxograph. The mean time to recovery of the first contraction of the train-of-four (T1) from 25% to 75% was significantly longer in the presence of doxapram (138 (SEM 21) s; n = 23) th...

متن کامل

Induction and emergence in infants less than 60 weeks post-conceptual age: comparison of thiopental, halothane, sevoflurane and desflurane.

We have studied 40 infants with a post-conceptual age of less than 60 weeks undergoing general anaesthesia for herniotomy. Patients were anaesthetized with 1 MAC equivalent values for age and agent and allocated randomly to receive halothane, savoflurane or thiopental for induction, and halothane, sevoflurane or desflurane for maintenance of anaesthesia. At induction, both time to acceptance of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Canadian Anaesthetists' Society journal

دوره 12  شماره 

صفحات  -

تاریخ انتشار 1965